Recently, the U.S. Department of Health and Human Services (HHS) released a statement announcing that some research has shown that acetaminophen, such as the brand Tylenol, can cause autism if taken during pregnancy.
In this article we address this, and other unfounded claims about autism.
Most Studies Do Not Support A Link Between Acetaminophen and Autism
Reaction to the HHS announcement was swift and united – acetaminophen does not cause autism.
Healthcare providers and scientists across the country, including Coralis Health co-founder Dr. Ayesha Cheema-Hasan, spoke out against this proclamation. They contend that not only is the autism-acetaminophen connection untrue, but the advice for pregnant women to withhold its use if needed, and to “tough it out”, is potentially dangerous.
The World Health Organization (WHO) also expressed concern, emphasizing that there is currently no conclusive scientific evidence confirming a possible link between autism and the use of acetaminophen (also known as paracetamol in some countries) during pregnancy.
While the studies cited in the HHS report show an association between autism and acetaminophen, the study does not prove causation. The study authors say more research is needed for a definitive answer. Other studies have found no such association.
In fact, the authors of one of the studies cited by HHS urge pregnant women not to stop taking acetaminophen without talking to their doctor, as untreated fever and pain can negatively affect the unborn baby.
It is also important to point out that acetaminophen is the only over-the-counter pain reliever and fever reducer that the FDA has approved for use during pregnancy. Other pain relievers such as ibuprofen and aspirin, collectively referred to as non-steroidal anti-inflammatory drugs or NSAIDs, are known to cause serious harm to developing babies. Of course, like any pain or fever reducing medication used by anyone, acetaminophen should only be used as necessary, at the lowest effective dose, and for the shortest amount of time needed, not to exceed recommended dosage guidelines.
Other Autism Myths – Vaccines and Leucovorin
Two other myths and misconceptions about autism that continue to circulate out there involve vaccines and Leucovorin (folinic acid).
The thought that vaccines cause autism has been around for a while, despite overwhelming evidence to the contrary. Vaccines do not cause autism. What vaccines have absolutely been proven to do is prevent disease, disability and death, in children and adults.
Another unfounded claim gaining traction is that Leucovorin cures autism. This is simply not true. While some small studies have shown it might help in communication or behavior, it’s not a cure. Treatment of autism with Leucovorin is considered off-label use, and we still need robust research to come to any conclusion about its effectiveness or risks.
Compounding the controversy surrounding Leucovorin, is use of the Folate Receptor Autoantibody Test (FRAT) to determine the effectiveness of Leucovorin therapy. Existing studies do not show that antibody assays will predict who responds to therapy. Despite the hype on social media platforms and marketing content by the test developer, using FRAT is unreliable and not helpful in Leucovorin therapy decision making. In addition, as with any unproven testing method, it is not covered by insurance.
Why Is Autism On The Rise?
The reason autism incidence is on the rise is not yet fully understood. While we know that things like vaccines and acetaminophen do not cause autism, the actual cause is the subject of intensive research. The cause is likely multifactorial, with genetics, environment, early screening, better classification, and accurate identification all playing a role.
Our Children Need Support, Not Stigma
The most important thing to know about autism is that it is not something to fix. Just like ADHD and other neurodivergent conditions, the brain is wired differently in children with autism. And just because it’s different doesn’t mean it’s bad. We need to understand and target autism-associated challenges. We need to focus on providing support, meeting children and families where they are and helping them thrive. Our kids deserve support, not stigma.
If you have questions about autism, please reach out to us at Coralis Health. Our highly qualified specialists are always here to help!
Reference Links:
Coralis Health’s Dr. Ayesha Cheema-Hasan Joins Panel of Experts Interview
ACOG Affirms Safety and Benefits of Acetaminophen During Pregnancy
AAP Statement on White House Autism Announcement
Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability
Vaccines Don’t Cause Autism. Why Do Some People Think They Do?
WHO Statement on Autism-Related Issues
